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Inhibitory Effect of b-AP15 on the 20S Proteasome

The 26S proteasome is a cellular proteolytic complex containing 19S regulatory particles and the 20S core proteasome. It was reported that the small molecule b-AP15 targets the proteasome by inhibiting deubiquitination of the 19S regulatory particles of the proteasome complex. An investigation of b-...

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Detalles Bibliográficos
Autores principales: Huang, Li, Jung, Katherine, Chen, Chin Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279163/
https://www.ncbi.nlm.nih.gov/pubmed/25317846
http://dx.doi.org/10.3390/biom4040931

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