Cargando…

Common Polymorphism in the LRP5 Gene May Increase the Risk of Bone Fracture and Osteoporosis

The low-density lipoprotein receptor-related protein 5 gene (LRP5) was identified to be linked to the variation in bone mineral density and types of bone diseases. The present study was aimed at examining the association of LRP5 rs3736228 C>T gene with bone fracture and osteoporosis by meta-analy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Guang-Yue, Qiu, Yong, Mao, Hai-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279179/ https://www.ncbi.nlm.nih.gov/pubmed/25580429 http://dx.doi.org/10.1155/2014/290531

Ejemplares similares

Associations of LRP5 Gene With Bone Mineral Density, Bone Turnover Markers, and Fractures in the Elderly With Osteoporosis
por: Wang, Qi-Fei, et al.
Publicado: (2020)

Osteoporosis, Fractures, and Blindness Due to a Missense Mutation in the LRP5 Receptor
por: Littman, Jake, et al.
Publicado: (2023)

LRP5, Bone Mass Polymorphisms and Skeletal Disorders
por: Littman, Jake, et al.
Publicado: (2023)

Polymorphisms of FDPS, LRP5, SOST and VKORC1 genes and their relation with osteoporosis in postmenopausal Romanian women
por: Ciubean, Alina Deniza, et al.
Publicado: (2019)

Identification of novel genes associated with fracture healing in osteoporosis induced by Krm2 overexpression or Lrp5 deficiency
por: Gao, Feng, et al.
Publicado: (2017)

Association of LRP5 genotypes with osteoporosis in Tunisian post-menopausal women
por: Sassi, Rim, et al.
Publicado: (2014)

Polymorphism of LRP4 Gene (rs9667108) among Post Menopause Women with Osteoporosis
por: Kavoosian, Saeid, et al.
Publicado: (2023)

Lrp5 p.Val667Met Variant Compromises Bone Mineral Density and Matrix Properties in Osteoporosis
por: Fabre, Stéphanie, et al.
Publicado: (2023)

Lrp5 functions in bone to regulate bone mass
por: Cui, Yajun, et al.
Publicado: (2011)

Where Wnts Went: The Exploding Field of Lrp5 and Lrp6 Signaling in Bone
por: Williams, Bart O, et al.
Publicado: (2009)

LRP5-/6 gene polymorphisms and its association with risk of abnormal bone mass in postmenopausal women
por: Li, Jun, et al.
Publicado: (2023)

Functional analysis of disease-associated polymorphism LRP5.Q89R
por: Mao, Weiming, et al.
Publicado: (2011)

Association between LRP5 polymorphism and bone mineral density: a Bayesian meta-analysis
por: Tran, Bich NH, et al.
Publicado: (2008)

Lrp5 and Lrp6 Exert Overlapping Functions in Osteoblasts during Postnatal Bone Acquisition
por: Riddle, Ryan C., et al.
Publicado: (2013)

Osteoporosis-Pseudoglioma in a Mauritanian Child due to a Novel Mutation in LRP5
por: Biha, Noura, et al.
Publicado: (2016)

Novel Homozygous Nonsense Mutation in the LRP5 Gene in Two Siblings with Osteoporosis-pseudoglioma Syndrome
por: Heidari, Abolfazl, et al.
Publicado: (2023)

LRP5-Mediated Lipid Uptake Modulates Osteogenic Differentiation of Bone Marrow Mesenchymal Stromal Cells
por: Lin, Jiachen, et al.
Publicado: (2021)

LRP5 and LRP6 in Wnt Signaling: Similarity and Divergence
por: Ren, Qian, et al.
Publicado: (2021)

The LRP6 rs2302685 polymorphism is associated with increased risk of myocardial infarction
por: Xu, Shun, et al.
Publicado: (2014)

Mutations in LRP5 cause primary osteoporosis without features of OI by reducing Wnt signaling activity
por: Korvala, Johanna, et al.
Publicado: (2012)

Common Variants in OPG Confer Risk to Bone Mineral Density Variation and Osteoporosis Fractures
por: Sheng, Xiaoyong, et al.
Publicado: (2017)

Polymorphism in autophagy-related genes LRP1 and CAPZA1 may promote gastric mucosal atrophy
por: Yamaguchi, Naoyuki, et al.
Publicado: (2023)

β-catenin-dependent High Bone Mass Induced by Loss of APC in Osteoblasts Does Not Require Lrp5 or Lrp6
por: Diegel, Cassandra R., et al.
Publicado: (2023)

For healthy eyes and bones: got Lrp?
por: Dove, Alan W.
Publicado: (2002)

Wise Regulates Bone Deposition through Genetic Interactions with Lrp5
por: Ellies, Debra L., et al.
Publicado: (2014)

A Study of the Relationship between the Polymorphism and Mutation of rs682429 and rs3781590 in the LRP5 Gene and Bone Metabolism in Postmenopausal Type 2 Diabetic Women in Xinjiang
por: Li, Jun, et al.
Publicado: (2020)

eys(+/-); lrp5(+/−) Zebrafish Reveals Lrp5 Can Be the Receptor of Retinol in the Visual Cycle
por: Takita, Shimpei, et al.
Publicado: (2020)

Dissecting Molecular Differences between Wnt Coreceptors LRP5 and LRP6
por: MacDonald, Bryan T., et al.
Publicado: (2011)

Vitamin D receptor gene polymorphisms, bone mineral density and fractures in postmenopausal women with osteoporosis
por: Horst-Sikorska, Wanda, et al.
Publicado: (2012)

Correction: Wise Regulates Bone Deposition through Genetic Interactions with Lrp5
Publicado: (2014)

Overexpression of Lrp5 enhanced the anti-breast cancer effects of osteocytes in bone
por: Liu, Shengzhi, et al.
Publicado: (2021)

The LRP1 Gene Polymorphism is associated with Increased Risk of Metabolic Syndrome Prevalence in the Serbian Population
por: Vučinić, N, et al.
Publicado: (2017)

Hyponatremia Is Associated With Increased Osteoporosis and Bone Fractures in Patients With Diabetes With Matched Glycemic Control
por: Usala, Rachel L, et al.
Publicado: (2019)

Influence of LRP5 (rs556442) polymorphism on insulin resistance in healthy Iranian children and adolescents
por: MONTAZERI-NAJAFABADY, Nima, et al.
Publicado: (2019)

Medical Care Use Among Patients with Monogenic Osteoporosis Due to Rare Variants in LRP5, PLS3, or WNT1
por: Verdonk, S. J. E., et al.
Publicado: (2023)

Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it
por: Saxon, Leanne K., et al.
Publicado: (2011)

LRP5, Bone Density, and Mechanical Stress: A Case Report and Literature Review
por: Norwitz, Nicholas G., et al.
Publicado: (2019)

Identification of Rare LRP5 Variants in a Cohort of Males with Impaired Bone Mass
por: Rocca, Maria Santa, et al.
Publicado: (2021)

Clinical relevance of genetic polymorphisms in WNT signaling pathway (SFRP1, WNT3A, CTNNB1, WIF-1, DKK-1, LRP5, LRP6) on pulmonary tuberculosis in a Chinese population
por: Huang, Qian, et al.
Publicado: (2022)

Hysterectomies are associated with an increased risk of osteoporosis and bone fracture: A population-based cohort study
por: Yeh, Ying-Ting, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_khegnmpfoc3nebes8k5lo146kg