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Cell survival is dicey without Dicer
The cellular requirements for Dicer, an essential miRNA processing enzyme, and the consequences of altered levels of its expression on tumorigenesis are incompletely understood. We review the effects of Dicer loss in cells of different origin and whether loss of p53 permits cell survival and growth...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279215/ https://www.ncbi.nlm.nih.gov/pubmed/25558471 http://dx.doi.org/10.4161/23723548.2014.961825 |