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A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase

Cohesin complex mediates cohesion between sister chromatids, which promotes high-fidelity chromosome segregation. Eco1p acetylates the cohesin subunit Smc3p during S phase to establish cohesion. The current model posits that this Eco1p-mediated acetylation promotes establishment by abrogating the ab...

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Detalles Bibliográficos
Autores principales: Guacci, Vincent, Stricklin, Jeremiah, Bloom, Michelle S., Guō, Xuánzōng, Bhatter, Meghna, Koshland, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279223/
https://www.ncbi.nlm.nih.gov/pubmed/25378582
http://dx.doi.org/10.1091/mbc.E14-08-1268