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A novel mechanism for the establishment of sister chromatid cohesion by the ECO1 acetyltransferase
Cohesin complex mediates cohesion between sister chromatids, which promotes high-fidelity chromosome segregation. Eco1p acetylates the cohesin subunit Smc3p during S phase to establish cohesion. The current model posits that this Eco1p-mediated acetylation promotes establishment by abrogating the ab...
Autores principales: | Guacci, Vincent, Stricklin, Jeremiah, Bloom, Michelle S., Guō, Xuánzōng, Bhatter, Meghna, Koshland, Douglas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279223/ https://www.ncbi.nlm.nih.gov/pubmed/25378582 http://dx.doi.org/10.1091/mbc.E14-08-1268 |
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