Cargando…
How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study
Metal-on-metal hip resurfacing (MOM-HR) is offered as an alternative to traditional hip arthroplasty for young, active adults with advanced osteoarthritis. Nevertheless, concerns remain regarding wear and corrosion of the bearing surfaces and the resulting increase in metal ion levels. We evaluated...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279264/ https://www.ncbi.nlm.nih.gov/pubmed/25580456 http://dx.doi.org/10.1155/2014/291925 |
_version_ | 1782350650092290048 |
---|---|
author | Savarino, Lucia Cadossi, Matteo Chiarello, Eugenio Fotia, Caterina Greco, Michelina Baldini, Nicola Giannini, Sandro |
author_facet | Savarino, Lucia Cadossi, Matteo Chiarello, Eugenio Fotia, Caterina Greco, Michelina Baldini, Nicola Giannini, Sandro |
author_sort | Savarino, Lucia |
collection | PubMed |
description | Metal-on-metal hip resurfacing (MOM-HR) is offered as an alternative to traditional hip arthroplasty for young, active adults with advanced osteoarthritis. Nevertheless, concerns remain regarding wear and corrosion of the bearing surfaces and the resulting increase in metal ion levels. We evaluated three cohorts of patients with Birmingham hip resurfacing (BHR) at an average follow-up of 2, 5, and 9 years. We asked whether there would be differences in ion levels between the cohorts and inside the gender. Nineteen patients were prospectively analyzed. The correlation with clinical-radiographic data was also performed. Chromium, cobalt, nickel, and molybdenum concentrations were measured by atomic absorption spectrophotometry. Chromium and cobalt levels demonstrated a tendency to decrease over time. Such tendency was present only in females. An inverse correlation between chromium, implant size, and Harris hip score was present at short term; it disappeared over time together with the decreased ion levels. The prospective analysis showed that, although metal ion levels remained fairly constant within each patient, there was a relatively large variation between subjects, so mean data in this scenario must be interpreted with caution. The chronic high exposure should be carefully considered during implant selection, particularly in young subjects, and a stricter monitoring is mandatory. |
format | Online Article Text |
id | pubmed-4279264 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-42792642015-01-11 How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study Savarino, Lucia Cadossi, Matteo Chiarello, Eugenio Fotia, Caterina Greco, Michelina Baldini, Nicola Giannini, Sandro ScientificWorldJournal Research Article Metal-on-metal hip resurfacing (MOM-HR) is offered as an alternative to traditional hip arthroplasty for young, active adults with advanced osteoarthritis. Nevertheless, concerns remain regarding wear and corrosion of the bearing surfaces and the resulting increase in metal ion levels. We evaluated three cohorts of patients with Birmingham hip resurfacing (BHR) at an average follow-up of 2, 5, and 9 years. We asked whether there would be differences in ion levels between the cohorts and inside the gender. Nineteen patients were prospectively analyzed. The correlation with clinical-radiographic data was also performed. Chromium, cobalt, nickel, and molybdenum concentrations were measured by atomic absorption spectrophotometry. Chromium and cobalt levels demonstrated a tendency to decrease over time. Such tendency was present only in females. An inverse correlation between chromium, implant size, and Harris hip score was present at short term; it disappeared over time together with the decreased ion levels. The prospective analysis showed that, although metal ion levels remained fairly constant within each patient, there was a relatively large variation between subjects, so mean data in this scenario must be interpreted with caution. The chronic high exposure should be carefully considered during implant selection, particularly in young subjects, and a stricter monitoring is mandatory. Hindawi Publishing Corporation 2014 2014-12-14 /pmc/articles/PMC4279264/ /pubmed/25580456 http://dx.doi.org/10.1155/2014/291925 Text en Copyright © 2014 Lucia Savarino et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Savarino, Lucia Cadossi, Matteo Chiarello, Eugenio Fotia, Caterina Greco, Michelina Baldini, Nicola Giannini, Sandro How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
title | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
title_full | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
title_fullStr | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
title_full_unstemmed | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
title_short | How Do Metal Ion Levels Change over Time in Hip Resurfacing Patients? A Cohort Study |
title_sort | how do metal ion levels change over time in hip resurfacing patients? a cohort study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279264/ https://www.ncbi.nlm.nih.gov/pubmed/25580456 http://dx.doi.org/10.1155/2014/291925 |
work_keys_str_mv | AT savarinolucia howdometalionlevelschangeovertimeinhipresurfacingpatientsacohortstudy AT cadossimatteo howdometalionlevelschangeovertimeinhipresurfacingpatientsacohortstudy AT chiarelloeugenio howdometalionlevelschangeovertimeinhipresurfacingpatientsacohortstudy AT fotiacaterina howdometalionlevelschangeovertimeinhipresurfacingpatientsacohortstudy AT grecomichelina howdometalionlevelschangeovertimeinhipresurfacingpatientsacohortstudy AT baldininicola howdometalionlevelschangeovertimeinhipresurfacingpatientsacohortstudy AT gianninisandro howdometalionlevelschangeovertimeinhipresurfacingpatientsacohortstudy |