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The evolution of spinal/epidural neostigmine in clinical application: Thoughts after two decades
Since the first clinical application of analgesia following spinal anticholinesterase by 1940's, several clinical double-blind studies have been conducted to date, where intrathecal doses of neostigmine in humans ranged from 750 to 1 μg, due to side-effects. Conversely, epidural neostigmine has...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279354/ https://www.ncbi.nlm.nih.gov/pubmed/25558203 http://dx.doi.org/10.4103/1658-354X.146319 |