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Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription
TET enzymes are the epigenetic factors involved in the formation of the sixth DNA base 5-hydroxymethylcytosine, whose deregulation has been associated with tumorigenesis. In particular, TET1 acts as tumor suppressor preventing cell proliferation and tumor metastasis and it has frequently been found...
Autores principales: | Ciccarone, Fabio, Valentini, Elisabetta, Bacalini, Maria Giulia, Zampieri, Michele, Calabrese, Roberta, Guastafierro, Tiziana, Mariano, Germano, Reale, Anna, Franceschi, Claudio, Caiafa, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279378/ https://www.ncbi.nlm.nih.gov/pubmed/24939750 |
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