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Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia

We have previously demonstrated that Tenascin-C (TNC)(+) human neuroblastoma (NB) cells transdifferentiate into tumor-derived endothelial cells (TDEC), which have been detected both in primary tumors and in tumors formed by human NB cell lines in immunodeficient mice. TDEC are genetically unstable a...

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Detalles Bibliográficos
Autores principales: Pezzolo, Annalisa, Marimpietri, Danilo, Raffaghello, Lizzia, Cocco, Claudia, Pistorio, Angela, Gambini, Claudio, Cilli, Michele, Horenstein, Alberto, Malavasi, Fabio, Pistoia, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279379/
https://www.ncbi.nlm.nih.gov/pubmed/25362644