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Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia
We have previously demonstrated that Tenascin-C (TNC)(+) human neuroblastoma (NB) cells transdifferentiate into tumor-derived endothelial cells (TDEC), which have been detected both in primary tumors and in tumors formed by human NB cell lines in immunodeficient mice. TDEC are genetically unstable a...
Autores principales: | Pezzolo, Annalisa, Marimpietri, Danilo, Raffaghello, Lizzia, Cocco, Claudia, Pistorio, Angela, Gambini, Claudio, Cilli, Michele, Horenstein, Alberto, Malavasi, Fabio, Pistoia, Vito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279379/ https://www.ncbi.nlm.nih.gov/pubmed/25362644 |
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