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H2AK119Ub1 and H3K27Me3 in molecular staging for survival prediction of patients with pancreatic ductal adenocarcinoma

Polycomb group (PcG) proteins Ring1B and EZH2, which have been characterized as catalyzing the two epigenetic modifications H2AK119 monoubiquitination (H2AK119Ub1) and H3K27 trimethylation (H3K27Me3), are well-known epigenetic silencers implicated in embryonic development and tumorigenesis. However,...

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Detalles Bibliográficos
Autores principales:	Chen, Shi, Chen, Jiangzhi, Zhan, Qian, Zhu, Yi, Chen, Hao, Deng, Xiaxing, Hou, Zhaoyuan, Shen, Baiyong, Chen, Yanling, Peng, Chenghong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279383/ https://www.ncbi.nlm.nih.gov/pubmed/25431952

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