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Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid
Glioblastomas are highly aggressive adult brain tumors with poor clinical outcome. In the central nervous system (CNS) the blood-brain barrier (BBB) is the most important limiting factor for both development of new drugs and drug delivery. Here, we propose a new strategy to treat glioblastoma based...
Autores principales: | Porru, Manuela, Zappavigna, Silvia, Salzano, Giuseppina, Luce, Amalia, Stoppacciaro, Antonella, Balestrieri, Maria Luisa, Artuso, Simona, Lusa, Sara, De Rosa, Giuseppe, Leonetti, Carlo, Caraglia, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279385/ https://www.ncbi.nlm.nih.gov/pubmed/25431953 |
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