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RNA-seq analysis reveals significant effects of EGFR signalling on the secretome of mesenchymal stem cells

Bone marrow-derived mesenchymal stem cells (MSCs) contribute to breast cancer progression by releasing soluble factors that sustain tumor progression. MSCs express functional epidermal growth factor receptor (EGFR) and breast cancer cells secrete EGFR-ligands including transforming growth factor-α (...

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Detalles Bibliográficos
Autores principales: De Luca, Antonella, Roma, Cristin, Gallo, Marianna, Fenizia, Francesca, Bergantino, Francesca, Frezzetti, Daniela, Costantini, Susan, Normanno, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279390/
https://www.ncbi.nlm.nih.gov/pubmed/25344915