SOX10, a novel HMG-box-containing tumor suppressor, inhibits growth and metastasis of digestive cancers by suppressing the Wnt/β-catenin pathway

SOX10 was identified as a methylated gene in our previous cancer methylome study. Here we further analyzed its epigenetic inactivation, biological functions and related cell signaling in digestive cancers (colorectal, gastric and esophageal cancers) in detail. SOX10 expression was decreased in multi...

Descripción completa

Detalles Bibliográficos
Autores principales: Tong, Xin, Li, Lili, Li, Xiaoyan, Heng, Lei, Zhong, Lan, Su, Xianwei, Rong, Rong, Hu, Shi, Liu, Wenjia, Jia, Baoqing, Liu, Xing, Kou, Geng, Han, Jun, Guo, Shangjing, Hu, Yi, Li, Cheng, Tao, Qian, Guo, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279394/
https://www.ncbi.nlm.nih.gov/pubmed/25301735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279394/
https://www.ncbi.nlm.nih.gov/pubmed/25301735

Ejemplares similares