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The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells
The p53 tumor suppressor protein plays a crucial role in influencing cell fate decisions in response to cellular stress. As p53 elicits cell cycle arrest, senescence or apoptosis, the integrity of the p53 pathway is considered a key determinant of anti-tumor responses. p53 can also promote autophagy...
Autores principales: | Ringer, Lymor, Sirajuddin, Paul, Tricoli, Lucas, Waye, Sarah, Choudhry, Muhammad Umer, Parasido, Erika, Sivakumar, Angiela, Heckler, Mary, Naeem, Aisha, Abdelgawad, Iman, Liu, Xuefeng, Feldman, Adam S., Lee, Richard J., Wu, Chin-Lee, Yenugonda, Venkata, Kallakury, Bhaskar, Dritschilo, Anatoly, Lynch, John, Schlegel, Richard, Rodriguez, Olga, Pestell, Richard G., Avantaggiati, Maria Laura, Albanese, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279402/ https://www.ncbi.nlm.nih.gov/pubmed/25296977 |
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