miR-145 inhibits tumor growth and metastasis by targeting metadherin in high-grade serous ovarian carcinoma

High-grade serous ovarian carcinoma (HGSOC), the most common and aggressive subtype of epithelial ovarian cancer, is characterized by TP53 mutations and genetic instability. Using miRNA profiling analysis, we found that miR-145, a p53 regulated miRNA, was frequently down-regulated in HGSOC. miR-145...

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Detalles Bibliográficos
Autores principales: Dong, Ruifen, Liu, Xiaolin, Zhang, Qing, Jiang, Zhijun, Li, Yingwei, Wei, Yuyan, Li, Yinuo, Yang, Qifeng, Liu, Jinsong, Wei, Jian-Jun, Shao, Changshun, Liu, Zhaojian, Kong, Beihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279412/
https://www.ncbi.nlm.nih.gov/pubmed/25333261

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