Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings

Hypertriglyceridemia (HTG) is a feature of numerous metabolic disorders including dyslipidemias, metabolic syndrome, and diabetes mellitus type 2 and can increase the risk of premature coronary artery disease. HTG may also be due to genetic factors (called primary HTG) and particularly the severe/ex...

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Autores principales: Diakoumakou, Olga, Hatzigeorgiou, Georgios, Gontoras, Nikos, Boutsikou, Maria, Kolovou, Vana, Mavrogeni, Sophie, Giannakopoulou, Vassiliki, Kolovou, Genovefa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279422/
https://www.ncbi.nlm.nih.gov/pubmed/25580288
http://dx.doi.org/10.1155/2014/109263
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author Diakoumakou, Olga
Hatzigeorgiou, Georgios
Gontoras, Nikos
Boutsikou, Maria
Kolovou, Vana
Mavrogeni, Sophie
Giannakopoulou, Vassiliki
Kolovou, Genovefa D.
author_facet Diakoumakou, Olga
Hatzigeorgiou, Georgios
Gontoras, Nikos
Boutsikou, Maria
Kolovou, Vana
Mavrogeni, Sophie
Giannakopoulou, Vassiliki
Kolovou, Genovefa D.
author_sort Diakoumakou, Olga
collection PubMed
description Hypertriglyceridemia (HTG) is a feature of numerous metabolic disorders including dyslipidemias, metabolic syndrome, and diabetes mellitus type 2 and can increase the risk of premature coronary artery disease. HTG may also be due to genetic factors (called primary HTG) and particularly the severe/extreme HTG (SEHTG), which is a usually rare genetic disorder. Even rarer are secondary cases of SEHTG caused by autoimmune disease. This review considers the causes of SEHTG, and their management including treatment with low density lipoprotein apheresis and analyzes the original findings.
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spelling pubmed-42794222015-01-11 Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings Diakoumakou, Olga Hatzigeorgiou, Georgios Gontoras, Nikos Boutsikou, Maria Kolovou, Vana Mavrogeni, Sophie Giannakopoulou, Vassiliki Kolovou, Genovefa D. Cholesterol Review Article Hypertriglyceridemia (HTG) is a feature of numerous metabolic disorders including dyslipidemias, metabolic syndrome, and diabetes mellitus type 2 and can increase the risk of premature coronary artery disease. HTG may also be due to genetic factors (called primary HTG) and particularly the severe/extreme HTG (SEHTG), which is a usually rare genetic disorder. Even rarer are secondary cases of SEHTG caused by autoimmune disease. This review considers the causes of SEHTG, and their management including treatment with low density lipoprotein apheresis and analyzes the original findings. Hindawi Publishing Corporation 2014 2014-12-16 /pmc/articles/PMC4279422/ /pubmed/25580288 http://dx.doi.org/10.1155/2014/109263 Text en Copyright © 2014 Olga Diakoumakou et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Diakoumakou, Olga
Hatzigeorgiou, Georgios
Gontoras, Nikos
Boutsikou, Maria
Kolovou, Vana
Mavrogeni, Sophie
Giannakopoulou, Vassiliki
Kolovou, Genovefa D.
Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings
title Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings
title_full Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings
title_fullStr Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings
title_full_unstemmed Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings
title_short Severe/Extreme Hypertriglyceridemia and LDL Apheretic Treatment: Review of the Literature, Original Findings
title_sort severe/extreme hypertriglyceridemia and ldl apheretic treatment: review of the literature, original findings
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279422/
https://www.ncbi.nlm.nih.gov/pubmed/25580288
http://dx.doi.org/10.1155/2014/109263
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