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Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small vessel disease

INTRODUCTION: Cerebral small vessel disease (cSVD) is one of the most prevalent neurological disorders. The progressive remodeling of brain microvessels due to arterial hypertension or other vascular risk factors causes subtle, but constant cognitive decline through to manifest dementia and substant...

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Detalles Bibliográficos
Autores principales:	Kaiser, Daniel, Weise, Gesa, Möller, Karoline, Scheibe, Johanna, Pösel, Claudia, Baasch, Sebastian, Gawlitza, Matthias, Lobsien, Donald, Diederich, Kai, Minnerup, Jens, Kranz, Alexander, Boltze, Johannes, Wagner, Daniel-Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279586/ https://www.ncbi.nlm.nih.gov/pubmed/25519173 http://dx.doi.org/10.1186/s40478-014-0169-8

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