Cargando…

CDK2-AP1 inhibits growth of breast cancer cells by regulating cell cycle and increasing docetaxel sensitivity in vivo and in vitro

BACKGROUND: Cell cycle regulatory pathway is a well-established pathway mainly dependent on cyclin-dependent kinases (CDKs), which are regulated positively by cyclins and negatively by cyclin-dependent kinase inhibitors(CKIs). Cyclin-dependent kinase 2 associate protein 1(CDK2-AP1) is a specific neg...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Xiangming, Xiang, Hua, Zong, Xiangyun, Yan, Xuebing, Yu, Yang, Liu, Guan, Zou, Dehong, Yang, Hongjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279590/
https://www.ncbi.nlm.nih.gov/pubmed/25550687
http://dx.doi.org/10.1186/s12935-014-0130-8