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CDK2-AP1 inhibits growth of breast cancer cells by regulating cell cycle and increasing docetaxel sensitivity in vivo and in vitro

BACKGROUND: Cell cycle regulatory pathway is a well-established pathway mainly dependent on cyclin-dependent kinases (CDKs), which are regulated positively by cyclins and negatively by cyclin-dependent kinase inhibitors(CKIs). Cyclin-dependent kinase 2 associate protein 1(CDK2-AP1) is a specific neg...

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Detalles Bibliográficos
Autores principales:	He, Xiangming, Xiang, Hua, Zong, Xiangyun, Yan, Xuebing, Yu, Yang, Liu, Guan, Zou, Dehong, Yang, Hongjian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279590/ https://www.ncbi.nlm.nih.gov/pubmed/25550687 http://dx.doi.org/10.1186/s12935-014-0130-8

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