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Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer
BACKGROUND: Pancreatic ductal adenocarcinoma has proven to be one of the most chemo-resistant among all solid organ malignancies. Several mechanisms of resistance have been described, though few reports of strategies to overcome this chemo-resistance have been successful in restoring sensitivity to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279680/ https://www.ncbi.nlm.nih.gov/pubmed/25499121 http://dx.doi.org/10.1186/s13046-014-0102-9 |