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Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma has proven to be one of the most chemo-resistant among all solid organ malignancies. Several mechanisms of resistance have been described, though few reports of strategies to overcome this chemo-resistance have been successful in restoring sensitivity to...

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Detalles Bibliográficos
Autores principales:	Daylami, Rouzbeh, Muilenburg, Diego J, Virudachalam, Subbulakshmi, Bold, Richard J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279680/ https://www.ncbi.nlm.nih.gov/pubmed/25499121 http://dx.doi.org/10.1186/s13046-014-0102-9

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