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Wilms’ tumor suppressor gene (WT1) suppresses apoptosis by transcriptionally downregulating BAX expression in immature rat granulosa cells

BACKGROUND: The important role of WT1 in early folliculogenesis was evident from its restricted expression pattern in immature follicles and from its involvement in transcriptional control of inhibin-α and FSH receptor. There is also considerable evidence that WT1 is a potent inhibitor of apoptotic...

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Detalles Bibliográficos
Autores principales: Park, Minji, Choi, Yuri, Choi, Hyeonhae, Roh, Jaesook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279686/
https://www.ncbi.nlm.nih.gov/pubmed/25491731
http://dx.doi.org/10.1186/s13048-014-0118-y