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Wilms’ tumor suppressor gene (WT1) suppresses apoptosis by transcriptionally downregulating BAX expression in immature rat granulosa cells
BACKGROUND: The important role of WT1 in early folliculogenesis was evident from its restricted expression pattern in immature follicles and from its involvement in transcriptional control of inhibin-α and FSH receptor. There is also considerable evidence that WT1 is a potent inhibitor of apoptotic...
Autores principales: | Park, Minji, Choi, Yuri, Choi, Hyeonhae, Roh, Jaesook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279686/ https://www.ncbi.nlm.nih.gov/pubmed/25491731 http://dx.doi.org/10.1186/s13048-014-0118-y |
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