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Antimullerian Hormone Changes after Laparoscopic Ovarian Cystectomy for Endometrioma Compared with the Nonovarian Conditions

Laparoscopic ovarian cystectomy is recommended for surgical procedure of endometrioma. The negative impact on ovarian reserve following removal had been documented. Little evidence had been reported for nonovarian originated effects. Objective. To evaluate the impact of laparoscopic ovarian cystecto...

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Autores principales: Tanprasertkul, Chamnan, Manusook, Sakol, Somprasit, Charintip, Ekarattanawong, Sophapun, Sreshthaputra, Opas, Vutyavanich, Teraporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279712/
https://www.ncbi.nlm.nih.gov/pubmed/25580291
http://dx.doi.org/10.1155/2014/654856
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author Tanprasertkul, Chamnan
Manusook, Sakol
Somprasit, Charintip
Ekarattanawong, Sophapun
Sreshthaputra, Opas
Vutyavanich, Teraporn
author_facet Tanprasertkul, Chamnan
Manusook, Sakol
Somprasit, Charintip
Ekarattanawong, Sophapun
Sreshthaputra, Opas
Vutyavanich, Teraporn
author_sort Tanprasertkul, Chamnan
collection PubMed
description Laparoscopic ovarian cystectomy is recommended for surgical procedure of endometrioma. The negative impact on ovarian reserve following removal had been documented. Little evidence had been reported for nonovarian originated effects. Objective. To evaluate the impact of laparoscopic ovarian cystectomy for endometrioma on ovarian reserve, measured by serum antimullerian hormone (AMH), compared to nonovarian pelvic surgery. Materials and Methods. A prospective study was conducted. Women who underwent laparoscopic ovarian cystectomy (LOC) and laparoscopic nonovarian pelvic surgery (NOS) were recruited and followed up through 6 months. Clinical baseline data and AMH were evaluated. Results. 39 and 38 participants were enrolled in LOC and NOS groups, respectively. Baseline characteristics (age, weight, BMI, and height) and preoperative AMH level between 2 groups were not statistically different. After surgery, AMH of both groups decreased since the first week, at 1 month and at 3 months. However, as compared to the LOC group at 6 months after operation, the mean AMH of the NOS group had regained its value with a highly significant difference. Conclusion. This study demonstrated the negative impact of nonovarian or indirect effects of laparoscopic surgery to ovarian reserve. The possible mechanisms are necessary for more investigations.
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spelling pubmed-42797122015-01-11 Antimullerian Hormone Changes after Laparoscopic Ovarian Cystectomy for Endometrioma Compared with the Nonovarian Conditions Tanprasertkul, Chamnan Manusook, Sakol Somprasit, Charintip Ekarattanawong, Sophapun Sreshthaputra, Opas Vutyavanich, Teraporn Minim Invasive Surg Research Article Laparoscopic ovarian cystectomy is recommended for surgical procedure of endometrioma. The negative impact on ovarian reserve following removal had been documented. Little evidence had been reported for nonovarian originated effects. Objective. To evaluate the impact of laparoscopic ovarian cystectomy for endometrioma on ovarian reserve, measured by serum antimullerian hormone (AMH), compared to nonovarian pelvic surgery. Materials and Methods. A prospective study was conducted. Women who underwent laparoscopic ovarian cystectomy (LOC) and laparoscopic nonovarian pelvic surgery (NOS) were recruited and followed up through 6 months. Clinical baseline data and AMH were evaluated. Results. 39 and 38 participants were enrolled in LOC and NOS groups, respectively. Baseline characteristics (age, weight, BMI, and height) and preoperative AMH level between 2 groups were not statistically different. After surgery, AMH of both groups decreased since the first week, at 1 month and at 3 months. However, as compared to the LOC group at 6 months after operation, the mean AMH of the NOS group had regained its value with a highly significant difference. Conclusion. This study demonstrated the negative impact of nonovarian or indirect effects of laparoscopic surgery to ovarian reserve. The possible mechanisms are necessary for more investigations. Hindawi Publishing Corporation 2014 2014-12-14 /pmc/articles/PMC4279712/ /pubmed/25580291 http://dx.doi.org/10.1155/2014/654856 Text en Copyright © 2014 Chamnan Tanprasertkul et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tanprasertkul, Chamnan
Manusook, Sakol
Somprasit, Charintip
Ekarattanawong, Sophapun
Sreshthaputra, Opas
Vutyavanich, Teraporn
Antimullerian Hormone Changes after Laparoscopic Ovarian Cystectomy for Endometrioma Compared with the Nonovarian Conditions
title Antimullerian Hormone Changes after Laparoscopic Ovarian Cystectomy for Endometrioma Compared with the Nonovarian Conditions
title_full Antimullerian Hormone Changes after Laparoscopic Ovarian Cystectomy for Endometrioma Compared with the Nonovarian Conditions
title_fullStr Antimullerian Hormone Changes after Laparoscopic Ovarian Cystectomy for Endometrioma Compared with the Nonovarian Conditions
title_full_unstemmed Antimullerian Hormone Changes after Laparoscopic Ovarian Cystectomy for Endometrioma Compared with the Nonovarian Conditions
title_short Antimullerian Hormone Changes after Laparoscopic Ovarian Cystectomy for Endometrioma Compared with the Nonovarian Conditions
title_sort antimullerian hormone changes after laparoscopic ovarian cystectomy for endometrioma compared with the nonovarian conditions
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279712/
https://www.ncbi.nlm.nih.gov/pubmed/25580291
http://dx.doi.org/10.1155/2014/654856
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