Cargando…
Tuberculin Skin Test Negativity Is Under Tight Genetic Control of Chromosomal Region 11p14-15 in Settings With Different Tuberculosis Endemicities
A substantial proportion of subjects exposed to a contagious tuberculosis case display lack of tuberculin skin test (TST) reactivity. We previously mapped a major locus (TST1) controlling lack of TST reactivity in families from an area in South Africa where tuberculosis is hyperendemic. Here, we con...
Autores principales: | Cobat, Aurélie, Poirier, Christine, Hoal, Eileen, Boland-Auge, Anne, de La Rocque, France, Corrard, François, Grange, Ghislain, Migaud, Mélanie, Bustamante, Jacinta, Boisson-Dupuis, Stéphanie, Casanova, Jean-Laurent, Schurr, Erwin, Alcaïs, Alexandre, Delacourt, Christophe, Abel, Laurent |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279780/ https://www.ncbi.nlm.nih.gov/pubmed/25143445 http://dx.doi.org/10.1093/infdis/jiu446 |
Ejemplares similares
-
Major Loci on Chromosomes 8q and 3q Control Interferon γ Production Triggered by Bacillus Calmette-Guerin and 6-kDa Early Secretory Antigen Target, Respectively, in Various Populations
por: Jabot-Hanin, Fabienne, et al.
Publicado: (2016) -
An eQTL variant of ZXDC is associated with IFN-γ production following Mycobacterium tuberculosis antigen-specific stimulation
por: Jabot-Hanin, Fabienne, et al.
Publicado: (2017) -
Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis
por: Cobat, Aurelie, et al.
Publicado: (2009) -
Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations
por: Quistrebert, Jocelyn, et al.
Publicado: (2021) -
Detection of homozygous and hemizygous complete or partial exon deletions by whole-exome sequencing
por: Bigio, Benedetta, et al.
Publicado: (2021)