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Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach

Aims. Increasing evidence shows that imbalanced suppressive drive prior to binocular combination may be the key factor in amblyopia. We described a novel binocular approach, interocular shift of visual attention (ISVA), for treatment of amblyopia in adult patients. Methods. Visual stimuli were prese...

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Autores principales: Huang, Liwen, Sun, Xinghuai, Luo, Gang, Liu, Shuai, Liu, Rui, Mansouri, Behzad, Wong, Vicky wing lai, Wen, Wen, Liu, Hong, Wang, Ai-Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279785/
https://www.ncbi.nlm.nih.gov/pubmed/25580280
http://dx.doi.org/10.1155/2014/615213
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author Huang, Liwen
Sun, Xinghuai
Luo, Gang
Liu, Shuai
Liu, Rui
Mansouri, Behzad
Wong, Vicky wing lai
Wen, Wen
Liu, Hong
Wang, Ai-Hou
author_facet Huang, Liwen
Sun, Xinghuai
Luo, Gang
Liu, Shuai
Liu, Rui
Mansouri, Behzad
Wong, Vicky wing lai
Wen, Wen
Liu, Hong
Wang, Ai-Hou
author_sort Huang, Liwen
collection PubMed
description Aims. Increasing evidence shows that imbalanced suppressive drive prior to binocular combination may be the key factor in amblyopia. We described a novel binocular approach, interocular shift of visual attention (ISVA), for treatment of amblyopia in adult patients. Methods. Visual stimuli were presented anaglyphically on a computer screen. A square target resembling Landolt C had 2 openings, one in red and one in cyan color. Through blue-red goggles, each eye could only see one of the two openings. The patient was required to report the location of the opening presented to the amblyopic eye. It started at an opening size of 800 sec of arc, went up and down in 160 sec of arc step, and stopped when reaching the 5th reversals. Ten patients with anisometropic amblyopia older than age 14 (average age: 26.7) were recruited and received ISVA treatment for 6 weeks, with 2 training sessions per day. Results. Both Titmus stereopsis (z = −2.809, P = 0.005) and Random-dot stereopsis (z = −2.317, P = 0.018) were significantly improved. Average improvement in best corrected visual acuity (BCVA) was 0.74 line (t = 5.842, P < 0.001). Conclusions. The ISVA treatment may be effective in treating amblyopia and restoring stereoscopic function.
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spelling pubmed-42797852015-01-11 Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach Huang, Liwen Sun, Xinghuai Luo, Gang Liu, Shuai Liu, Rui Mansouri, Behzad Wong, Vicky wing lai Wen, Wen Liu, Hong Wang, Ai-Hou J Ophthalmol Clinical Study Aims. Increasing evidence shows that imbalanced suppressive drive prior to binocular combination may be the key factor in amblyopia. We described a novel binocular approach, interocular shift of visual attention (ISVA), for treatment of amblyopia in adult patients. Methods. Visual stimuli were presented anaglyphically on a computer screen. A square target resembling Landolt C had 2 openings, one in red and one in cyan color. Through blue-red goggles, each eye could only see one of the two openings. The patient was required to report the location of the opening presented to the amblyopic eye. It started at an opening size of 800 sec of arc, went up and down in 160 sec of arc step, and stopped when reaching the 5th reversals. Ten patients with anisometropic amblyopia older than age 14 (average age: 26.7) were recruited and received ISVA treatment for 6 weeks, with 2 training sessions per day. Results. Both Titmus stereopsis (z = −2.809, P = 0.005) and Random-dot stereopsis (z = −2.317, P = 0.018) were significantly improved. Average improvement in best corrected visual acuity (BCVA) was 0.74 line (t = 5.842, P < 0.001). Conclusions. The ISVA treatment may be effective in treating amblyopia and restoring stereoscopic function. Hindawi Publishing Corporation 2014 2014-12-15 /pmc/articles/PMC4279785/ /pubmed/25580280 http://dx.doi.org/10.1155/2014/615213 Text en Copyright © 2014 Liwen Huang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Huang, Liwen
Sun, Xinghuai
Luo, Gang
Liu, Shuai
Liu, Rui
Mansouri, Behzad
Wong, Vicky wing lai
Wen, Wen
Liu, Hong
Wang, Ai-Hou
Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach
title Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach
title_full Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach
title_fullStr Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach
title_full_unstemmed Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach
title_short Interocular Shift of Visual Attention Enhances Stereopsis and Visual Acuities of Anisometropic Amblyopes beyond the Critical Period of Visual Development: A Novel Approach
title_sort interocular shift of visual attention enhances stereopsis and visual acuities of anisometropic amblyopes beyond the critical period of visual development: a novel approach
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279785/
https://www.ncbi.nlm.nih.gov/pubmed/25580280
http://dx.doi.org/10.1155/2014/615213
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