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Inhibition of porcine reproductive and respiratory syndrome virus infection by recombinant adenovirus- and/or exosome-delivered the artificial microRNAs targeting sialoadhesin and CD163 receptors

BACKGROUND: The current vaccines failed to provide substantial protection against porcine reproductive and respiratory syndrome (PRRS) and the new vaccine development faces great challenges. Sialoadhesin (Sn) and CD163 are the two key receptors for PRRS virus (PRRSV) infection of porcine alveolar ma...

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Detalles Bibliográficos
Autores principales:	Zhu, Li, Song, Hongqin, Zhang, Xinyu, Xia, Xiaoli, Sun, Huaichang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279792/ https://www.ncbi.nlm.nih.gov/pubmed/25522782 http://dx.doi.org/10.1186/s12985-014-0225-9

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