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Bisphosphonate therapy in pediatric patients
Although for many decades bisphosphonates were used for adult bone loss, bisphosphonate administration in pediatric patients is new and was initiated in the past 15-year. The indications for pediatric bisphosphonates was extended to childhood malignancies with bone involvement, after additional effe...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279811/ https://www.ncbi.nlm.nih.gov/pubmed/25551100 http://dx.doi.org/10.1186/s40200-014-0109-y |
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| author | Eghbali-Fatourechi, Guiti |
| author_facet | Eghbali-Fatourechi, Guiti |
| author_sort | Eghbali-Fatourechi, Guiti |
| collection | PubMed |
| description | Although for many decades bisphosphonates were used for adult bone loss, bisphosphonate administration in pediatric patients is new and was initiated in the past 15-year. The indications for pediatric bisphosphonates was extended to childhood malignancies with bone involvement, after additional effects were unveiled for bisphosphonates with recent research. In this article we review childhood bone loss and conditions with bone involvement in which bisphosphonate therapy have been used. We also review mechanisms of action of bisphosphonates, and present indications of bisphosphonate therapy in pediatric patients based on results of clinical trials. |
| format | Online Article Text |
| id | pubmed-4279811 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-42798112014-12-31 Bisphosphonate therapy in pediatric patients Eghbali-Fatourechi, Guiti J Diabetes Metab Disord Review Article Although for many decades bisphosphonates were used for adult bone loss, bisphosphonate administration in pediatric patients is new and was initiated in the past 15-year. The indications for pediatric bisphosphonates was extended to childhood malignancies with bone involvement, after additional effects were unveiled for bisphosphonates with recent research. In this article we review childhood bone loss and conditions with bone involvement in which bisphosphonate therapy have been used. We also review mechanisms of action of bisphosphonates, and present indications of bisphosphonate therapy in pediatric patients based on results of clinical trials. BioMed Central 2014-12-17 /pmc/articles/PMC4279811/ /pubmed/25551100 http://dx.doi.org/10.1186/s40200-014-0109-y Text en © Eghbali-Fatourechi; licensee BioMed Central. 2014 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Review Article Eghbali-Fatourechi, Guiti Bisphosphonate therapy in pediatric patients |
| title | Bisphosphonate therapy in pediatric patients |
| title_full | Bisphosphonate therapy in pediatric patients |
| title_fullStr | Bisphosphonate therapy in pediatric patients |
| title_full_unstemmed | Bisphosphonate therapy in pediatric patients |
| title_short | Bisphosphonate therapy in pediatric patients |
| title_sort | bisphosphonate therapy in pediatric patients |
| topic | Review Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279811/ https://www.ncbi.nlm.nih.gov/pubmed/25551100 http://dx.doi.org/10.1186/s40200-014-0109-y |
| work_keys_str_mv | AT eghbalifatourechiguiti bisphosphonatetherapyinpediatricpatients |