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The GLP-1 Analogue Exenatide Improves Hepatic and Muscle Insulin Sensitivity in Diabetic Rats: Tracer Studies in the Basal State and during Hyperinsulinemic-Euglycemic Clamp
Objective. Glucagon-like peptide-1 (GLP-1) analogues (e.g., exenatide) increase insulin secretion in diabetes but less is known about their effects on glucose production or insulin-stimulated glucose uptake in peripheral tissues. Methods. Four groups of Sprague-Dawley rats were studied: nondiabetic...
Autores principales: | Wu, Hui, Sui, Chunhua, Xu, Hui, Xia, Fangzhen, Zhai, Hualing, Zhang, Huixin, Weng, Pan, Han, Bing, Du, Sichun, Lu, Yingli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279913/ https://www.ncbi.nlm.nih.gov/pubmed/25580440 http://dx.doi.org/10.1155/2014/524517 |
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