Robust dose-response curve estimation applied to high content screening data analysis

BACKGROUND AND METHOD: Successfully automated sigmoidal curve fitting is highly challenging when applied to large data sets. In this paper, we describe a robust algorithm for fitting sigmoid dose-response curves by estimating four parameters (floor, window, shift, and slope), together with the detec...

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Detalles Bibliográficos
Autores principales: Nguyen, Thuy Tuong, Song, Kyungmin, Tsoy, Yury, Kim, Jin Yeop, Kwon, Yong-Jun, Kang, Myungjoo, Edberg Hansen, Michael Adsetts
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279979/
https://www.ncbi.nlm.nih.gov/pubmed/25614758
http://dx.doi.org/10.1186/s13029-014-0027-x

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