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Proprotein convertase subtilisin/kexin type 9 expression is transiently up-regulated in the acute period of myocardial infarction in rat

BACKGROUND: The proprotein convertase subtilisin/kexin type 9 (PCSK9) has been confirmed as a major factor regulating cholesterol homeostasis and has low-density lipoprotein receptor (LDLR) independent effects. In addition, the pathogenesis of acute myocardial infarction (AMI) involves lipids altera...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Liu, Jun, Li, Sha, Xu, Rui-Xia, Sun, Jing, Tang, Yue, Li, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279995/
https://www.ncbi.nlm.nih.gov/pubmed/25519174
http://dx.doi.org/10.1186/1471-2261-14-192