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LC–MS/MS determination and pharmacokinetic study of columbianadin in rat plasma after intravenous administration of pure columbianadin

BACKGROUND: Columbianadin, one of the active coumarins, is isolated from Radix Angelicae pubescentis which has been used as a traditional Chinese medicine for the treatment of rheumatic diseases for thousands of years. A fast and sensitive method is required for the determination of columbianadin fo...

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Detalles Bibliográficos
Autores principales:	Chang, Yan-xu, Wang, Chun-peng, Li, Jin, Bai, Yang, Luo, Qian, He, Jun, Lu, Bing, Wang, Tao, Zhang, Bo-li, Gao, Xiu-mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280029/ https://www.ncbi.nlm.nih.gov/pubmed/25550710 http://dx.doi.org/10.1186/s13065-014-0064-1

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