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On the Modularity of the Intrinsic Flexibility of the µ Opioid Receptor: A Computational Study
The µ opioid receptor (µOR), the principal target to control pain, belongs to the G protein-coupled receptors (GPCRs) family, one of the most highlighted protein families due to their importance as therapeutic targets. The conformational flexibility of GPCRs is one of their essential characteristics...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280117/ https://www.ncbi.nlm.nih.gov/pubmed/25549261 http://dx.doi.org/10.1371/journal.pone.0115856 |