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Role of High Mobility Group Box 1 (HMGB1) in SCA17 Pathogenesis

Spinocerebellar ataxia type 17 (SCA17) involves the expression of a polyglutamine (polyQ) expanded TATA-binding protein (TBP), a general transcription initiation factor. TBP interacts with other protein factors, including high mobility group box 1 (HMGB1), to regulate gene expression. Previously, ou...

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Detalles Bibliográficos
Autores principales:	Lee, Li-Ching, Chen, Chiung-Mei, Wang, Pin-Rong, Su, Ming-Tsan, Lee-Chen, Guey-Jen, Chang, Chun-Yen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280131/ https://www.ncbi.nlm.nih.gov/pubmed/25549101 http://dx.doi.org/10.1371/journal.pone.0115809

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