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Broad Adaptive Immune Responses to M. tuberculosis Antigens Precede TST Conversion in Tuberculosis Exposed Household Contacts in a TB-Endemic Setting

BACKGROUND: The identification of Mycobacterium(-)tuberculosis (Mtb) infected individuals remains a challenge due to an insufficient understanding of immune responses detected with the current diagnostic tests for latent tuberculosis i.e. the tuberculin skin test (TST) or IFN–γ release assays (IGRAs...

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Detalles Bibliográficos
Autores principales:	Buchwald, Ulrike K., Adetifa, Ifedayo M. O., Bottomley, Christian, Owiafe, Patrick K., Donkor, Simon, Bojang, Adama L., Sutherland, Jayne S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280211/ https://www.ncbi.nlm.nih.gov/pubmed/25549338 http://dx.doi.org/10.1371/journal.pone.0116268

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