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Dietary intake and ghrelin and leptin changes after sleeve gastrectomy

INTRODUCTION: Surgical intervention in obesity is today the most effective treatment method in high level obesity management. Bariatric interventions not only ensure body weight reduction, but may influence dietary habits. AIM: To assess changes in adipose hormones and dietary habits in obese patien...

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Autores principales: Bužga, Marek, Zavadilová, Vladislava, Holéczy, Pavol, Švagera, Zdeněk, Švorc, Pavol, Foltys, Aleš, Zonča, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280419/
https://www.ncbi.nlm.nih.gov/pubmed/25561993
http://dx.doi.org/10.5114/wiitm.2014.45437
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author Bužga, Marek
Zavadilová, Vladislava
Holéczy, Pavol
Švagera, Zdeněk
Švorc, Pavol
Foltys, Aleš
Zonča, Pavel
author_facet Bužga, Marek
Zavadilová, Vladislava
Holéczy, Pavol
Švagera, Zdeněk
Švorc, Pavol
Foltys, Aleš
Zonča, Pavel
author_sort Bužga, Marek
collection PubMed
description INTRODUCTION: Surgical intervention in obesity is today the most effective treatment method in high level obesity management. Bariatric interventions not only ensure body weight reduction, but may influence dietary habits. AIM: To assess changes in adipose hormones and dietary habits in obese patients after sleeve gastrectomy. MATERIAL AND METHODS: The study set comprised 37 subjects (29 females and 8 males) 24 to 68 years old with body mass index 43.0 ±4.9 kg/m(2). Pre-operative examination included baseline measurements of body composition. Dietary habits and intake frequency were monitored by a questionnaire method. Follow-up examinations were carried out in a scope identical to the pre-operative examination, 6 and 12 months after surgery, respectively. RESULTS: The average patient weight loss 12 months after surgery was 31.7 kg. Excess weight loss was 55.2 ±20.6%. Patients reported reduced appetite (p < 0.001), increasingly regular food intake (p < 0.001), intake of more meal portions per day (p = 0.003) and a decrease in consuming the largest portions during the afternoon and evening (p = 0.030). Plasma levels of fasting glucose, leptin and ghrelin significantly decreased (p = 0.006; p = 0.0.043); in contrast, the level of adiponectin significantly increased (p < 0.001). CONCLUSIONS: Sleeve gastrectomy and follow-up nutritional therapy resulted in a significant body weight reduction within 1 year after surgery. An improvement of certain dietary habits in patients was registered. At 12 months after surgery, there were no statistically significant differences in decreases in ghrelin and leptin concentrations between patients without changed appetite and those reporting decreased appetite.
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spelling pubmed-42804192015-01-05 Dietary intake and ghrelin and leptin changes after sleeve gastrectomy Bužga, Marek Zavadilová, Vladislava Holéczy, Pavol Švagera, Zdeněk Švorc, Pavol Foltys, Aleš Zonča, Pavel Wideochir Inne Tech Maloinwazyjne Original Paper INTRODUCTION: Surgical intervention in obesity is today the most effective treatment method in high level obesity management. Bariatric interventions not only ensure body weight reduction, but may influence dietary habits. AIM: To assess changes in adipose hormones and dietary habits in obese patients after sleeve gastrectomy. MATERIAL AND METHODS: The study set comprised 37 subjects (29 females and 8 males) 24 to 68 years old with body mass index 43.0 ±4.9 kg/m(2). Pre-operative examination included baseline measurements of body composition. Dietary habits and intake frequency were monitored by a questionnaire method. Follow-up examinations were carried out in a scope identical to the pre-operative examination, 6 and 12 months after surgery, respectively. RESULTS: The average patient weight loss 12 months after surgery was 31.7 kg. Excess weight loss was 55.2 ±20.6%. Patients reported reduced appetite (p < 0.001), increasingly regular food intake (p < 0.001), intake of more meal portions per day (p = 0.003) and a decrease in consuming the largest portions during the afternoon and evening (p = 0.030). Plasma levels of fasting glucose, leptin and ghrelin significantly decreased (p = 0.006; p = 0.0.043); in contrast, the level of adiponectin significantly increased (p < 0.001). CONCLUSIONS: Sleeve gastrectomy and follow-up nutritional therapy resulted in a significant body weight reduction within 1 year after surgery. An improvement of certain dietary habits in patients was registered. At 12 months after surgery, there were no statistically significant differences in decreases in ghrelin and leptin concentrations between patients without changed appetite and those reporting decreased appetite. Termedia Publishing House 2014-09-23 2014-12 /pmc/articles/PMC4280419/ /pubmed/25561993 http://dx.doi.org/10.5114/wiitm.2014.45437 Text en Copyright © 2014 Sekcja Wideochirurgii TChP http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Bužga, Marek
Zavadilová, Vladislava
Holéczy, Pavol
Švagera, Zdeněk
Švorc, Pavol
Foltys, Aleš
Zonča, Pavel
Dietary intake and ghrelin and leptin changes after sleeve gastrectomy
title Dietary intake and ghrelin and leptin changes after sleeve gastrectomy
title_full Dietary intake and ghrelin and leptin changes after sleeve gastrectomy
title_fullStr Dietary intake and ghrelin and leptin changes after sleeve gastrectomy
title_full_unstemmed Dietary intake and ghrelin and leptin changes after sleeve gastrectomy
title_short Dietary intake and ghrelin and leptin changes after sleeve gastrectomy
title_sort dietary intake and ghrelin and leptin changes after sleeve gastrectomy
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280419/
https://www.ncbi.nlm.nih.gov/pubmed/25561993
http://dx.doi.org/10.5114/wiitm.2014.45437
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