Occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later

Methylene blue is utilized as the main treatment of methemoglobinemia. Here we report two cases, in which patient suffered from aniline-induced methemoglobinemia with initial good response but later developed haemolytic anemia due to methylene blue therapy. He was treated with hydration, high flow o...

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Autores principales: Ravi Kumar, YS, Manthappa, Kumar, Prasanna, Prasad, MC, Radhika, AR, Edara, Amarendra Chowdary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280784/
https://www.ncbi.nlm.nih.gov/pubmed/25568605
http://dx.doi.org/10.4103/0019-5278.146899
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author Ravi Kumar, YS
Manthappa,
Kumar, Prasanna
Prasad, MC
Radhika, AR
Edara, Amarendra Chowdary
author_facet Ravi Kumar, YS
Manthappa,
Kumar, Prasanna
Prasad, MC
Radhika, AR
Edara, Amarendra Chowdary
author_sort Ravi Kumar, YS
collection PubMed
description Methylene blue is utilized as the main treatment of methemoglobinemia. Here we report two cases, in which patient suffered from aniline-induced methemoglobinemia with initial good response but later developed haemolytic anemia due to methylene blue therapy. He was treated with hydration, high flow oxygen and steroid therapy. Caution should be exercised while using methylene blue as antidote of acute methemoglobinemia as both methemoglobinemia and its antidote methylene blue can itself precipitate fatal haemolytic anemia.
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spelling pubmed-42807842015-01-07 Occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later Ravi Kumar, YS Manthappa, Kumar, Prasanna Prasad, MC Radhika, AR Edara, Amarendra Chowdary Indian J Occup Environ Med Case Report Methylene blue is utilized as the main treatment of methemoglobinemia. Here we report two cases, in which patient suffered from aniline-induced methemoglobinemia with initial good response but later developed haemolytic anemia due to methylene blue therapy. He was treated with hydration, high flow oxygen and steroid therapy. Caution should be exercised while using methylene blue as antidote of acute methemoglobinemia as both methemoglobinemia and its antidote methylene blue can itself precipitate fatal haemolytic anemia. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4280784/ /pubmed/25568605 http://dx.doi.org/10.4103/0019-5278.146899 Text en Copyright: © Indian Journal of Occupational and Environmental Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ravi Kumar, YS
Manthappa,
Kumar, Prasanna
Prasad, MC
Radhika, AR
Edara, Amarendra Chowdary
Occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later
title Occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later
title_full Occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later
title_fullStr Occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later
title_full_unstemmed Occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later
title_short Occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later
title_sort occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280784/
https://www.ncbi.nlm.nih.gov/pubmed/25568605
http://dx.doi.org/10.4103/0019-5278.146899
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