Age-related variations in the methylome associated with gene expression in human monocytes and T cells

Age-related variations in DNA methylation have been reported; however, the functional relevance of these differentially methylated sites (age-dMS) are unclear. Here we report potentially functional age-dMS, defined as age- and cis-gene expression-associated methylation sites (age-eMS), identified by...

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Detalles Bibliográficos
Autores principales: Reynolds, Lindsay M., Taylor, Jackson R., Ding, Jingzhong, Lohman, Kurt, Johnson, Craig, Siscovick, David, Burke, Gregory, Post, Wendy, Shea, Steven, Jacobs, David R., Stunnenberg, Hendrik, Kritchevsky, Stephen B., Hoeschele, Ina, McCall, Charles E., Herrington, David, Tracy, Russell P., Liu, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280798/
https://www.ncbi.nlm.nih.gov/pubmed/25404168
http://dx.doi.org/10.1038/ncomms6366

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