Cargando…

Mirror-Image Organometallic Osmium Arene Iminopyridine Halido Complexes Exhibit Similar Potent Anticancer Activity

Four chiral Os(II) arene anticancer complexes have been isolated by fractional crystallization. The two iodido complexes, (S(Os),S(C))-[Os(η(6)-p-cym)(ImpyMe)I]PF(6) (complex 2, (S)-ImpyMe: N-(2-pyridylmethylene)-(S)-1-phenylethylamine) and (R(Os),R(C))-[Os(η(6)-p-cym)(ImpyMe)I]PF(6) (complex 4, (R)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Ying, Soni, Rina, Romero, María J, Pizarro, Ana M, Salassa, Luca, Clarkson, Guy J, Hearn, Jessica M, Habtemariam, Abraha, Wills, Martin, Sadler, Peter J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2013
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280897/ https://www.ncbi.nlm.nih.gov/pubmed/24114923 http://dx.doi.org/10.1002/chem.201302183

Ejemplares similares

Photorelease of Pyridyl Esters in Organometallic Ru(II) Arene Complexes
por: Habtemariam, Abraha, et al.
Publicado: (2015)

Half-Sandwich Arene Ruthenium(II) and Osmium(II) Thiosemicarbazone Complexes: Solution Behavior and Antiproliferative Activity
por: Gatti, Anna, et al.
Publicado: (2018)

Organometallic cis-Dichlorido Ruthenium(II) Ammine Complexes
por: Betanzos-Lara, Soledad, et al.
Publicado: (2011)

Easy To Synthesize, Robust Organo‐osmium Asymmetric Transfer Hydrogenation Catalysts
por: Coverdale, James P. C., et al.
Publicado: (2015)

NMR studies of group 8 metallodrugs: (187)Os-enriched organo-osmium half-sandwich anticancer complex
por: Needham, Russell J., et al.
Publicado: (2021)

In‐Cell Activation of Organo‐Osmium(II) Anticancer Complexes
por: Needham, Russell J., et al.
Publicado: (2016)

Halide Control of N,N-Coordination versus N,C-Cyclometalation and Stereospecific Phenyl Ring Deuteration of Osmium(II) p-Cymene Phenylazobenzothiazole Complexes
por: Needham, Russell J., et al.
Publicado: (2017)

The Potent Oxidant Anticancer Activity of Organoiridium Catalysts**
por: Liu, Zhe, et al.
Publicado: (2014)

Osmium–arene complexes with high potency towards Mycobacterium tuberculosis
por: Coverdale, James P C, et al.
Publicado: (2021)

Osmium(ii) tethered half-sandwich complexes: pH-dependent aqueous speciation and transfer hydrogenation in cells
por: Infante-Tadeo, Sonia, et al.
Publicado: (2021)

Direct Formation of Tethered Ru(II) Catalysts Using Arene Exchange
por: Soni, Rina, et al.
Publicado: (2013)

Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C(∧)N-Chelated and Pyridine Ligands
por: Liu, Zhe, et al.
Publicado: (2014)

New activation mechanism for half-sandwich organometallic anticancer complexes
por: Banerjee, Samya, et al.
Publicado: (2018)

Unconventional Approaches in Coordination Chemistry and Organometallic Reactivity
por: Salassa, Giovanni, et al.
Publicado: (2021)

Os(2)–Os(4) Switch Controls DNA Knotting and Anticancer Activity
por: Fu, Ying, et al.
Publicado: (2016)

Osmium Arene Germyl, Stannyl, Germanate, and Stannate Complexes as Anticancer Agents
por: Nabiyeva, Tomiris, et al.
Publicado: (2021)

Platinum(iv) dihydroxido diazido N-(heterocyclic)imine complexes are potently photocytotoxic when irradiated with visible light
por: Shaili, Evyenia, et al.
Publicado: (2019)

In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer
por: Aird, R E, et al.
Publicado: (2002)

Platinum(iv)-azido monocarboxylato complexes are photocytotoxic under irradiation with visible light
por: Shaili, Evyenia, et al.
Publicado: (2021)

Biological activity of ruthenium and osmium arene complexes with modified paullones in human cancer cells
por: Mühlgassner, Gerhard, et al.
Publicado: (2012)

Tracking Reactions of Asymmetric Organo‐Osmium Transfer Hydrogenation Catalysts in Cancer Cells
por: Bolitho, Elizabeth M., et al.
Publicado: (2021)

Crystal structures of five halido gold complexes involving piperidine or pyrrolidine as ligands or (protonated) as cations
por: Döring, Cindy, et al.
Publicado: (2023)

Contrasting Anticancer Activity of Half-Sandwich Iridium(III) Complexes Bearing Functionally Diverse 2-Phenylpyridine Ligands
por: Millett, Adam J., et al.
Publicado: (2015)

Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity
por: Smith, Nichola A., et al.
Publicado: (2017)

Enhancing the Activity of Drugs by Conjugation to Organometallic Fragments
por: Chellan, Prinessa, et al.
Publicado: (2020)

Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes
por: Hanif, Muhammad, et al.
Publicado: (2013)

Organometallic Iridium(III) Anticancer Complexes with New Mechanisms of Action: NCI-60 Screening, Mitochondrial Targeting, and Apoptosis
por: Hearn, Jessica M., et al.
Publicado: (2013)

Influences of Fluorine Substituents on Iminopyridine Fe(II)- and Co(II)-Catalyzed Isoprene Polymerization
por: Zhu, Guangqian, et al.
Publicado: (2018)

Correction to Organometallic Iridium(III) Anticancer Complexes with New Mechanisms of Action: NCI-60 Screening, Mitochondrial Targeting, and Apoptosis
por: Hearn, Jessica M., et al.
Publicado: (2013)

Enhancement of Selectivity of an Organometallic Anticancer Agent by Redox Modulation
por: Romero-Canelón, Isolda, et al.
Publicado: (2015)

A Breast Cancer Stem Cell-Selective, Mammospheres-Potent Osmium(VI) Nitrido Complex
por: Suntharalingam, Kogularamanan, et al.
Publicado: (2014)

Influences of Alkyl and Aryl Substituents on Iminopyridine Fe(II)- and Co(II)-Catalyzed Isoprene Polymerization
por: Guo, Lihua, et al.
Publicado: (2016)

Isoprene Polymerization: Catalytic Performance of Iminopyridine Vanadium(III) Chloride versus Vanadium(III) Chloride
por: Zhao, Mengmeng, et al.
Publicado: (2019)

Vapor Pressures of Ruthenium and Osmium
por: Carrera, N. J., et al.
Publicado: (1964)

Radiosensitisation of human colorectal cancer cells by ruthenium(II) arene anticancer complexes
por: Carter, R, et al.
Publicado: (2016)

Medicinal Hypervalent Tellurium Prodrugs Bearing Different Ligands: A Comparative Study of the Chemical Profiles of AS101 and Its Halido Replaced Analogues
por: Chiaverini, Lorenzo, et al.
Publicado: (2022)

Transfer Hydrogenation and Antiproliferative Activity of Tethered Half-Sandwich Organoruthenium Catalysts
por: Chen, Feng, et al.
Publicado: (2018)

Ruthenium− and Osmium−Arene Complexes of 2-Substituted Indolo[3,2-c]quinolines: Synthesis, Structure, Spectroscopic Properties, and Antiproliferative Activity
por: Filak, Lukas K., et al.
Publicado: (2010)

Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design
por: Soldevila-Barreda, Joan J., et al.
Publicado: (2015)

Dinuclear Iron Complexes of Iminopyridine-Based Ligands as Selective Cytotoxins for Tumor Cells and Inhibitors of Cancer Cell Migration
por: Castro, Jessica, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_674cbbgj7hvb6q1tsg5kso7tpq