Systematic Analysis of Fly Models with Multiple Drivers Reveals Different Effects of Ataxin-1 and Huntingtin in Neuron Subtype-Specific Expression

The fruit fly, Drosophila melanogaster, is a commonly used model organism for neurodegenerative diseases. Its major advantages include a short lifespan and its susceptibility to manipulation using sophisticated genetic techniques. Here, we report the systematic comparison of fly models of two polygl...

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Detalles Bibliográficos
Autores principales: Shiraishi, Risa, Tamura, Takuya, Sone, Masaki, Okazawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281079/
https://www.ncbi.nlm.nih.gov/pubmed/25551764
http://dx.doi.org/10.1371/journal.pone.0116567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281079/
https://www.ncbi.nlm.nih.gov/pubmed/25551764
http://dx.doi.org/10.1371/journal.pone.0116567

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