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pH-Dependent Conformational Changes in the HCV NS3 Protein Modulate Its ATPase and Helicase Activities

The hepatitis C virus (HCV) infects 170 to 200 million people worldwide and is, therefore, a major health problem. The lack of efficient treatments that specifically target the viral proteins or RNA and its high chronicity rate make hepatitis C the cause of many deaths and hepatic transplants annual...

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Detalles Bibliográficos
Autores principales:	Ventura, Gustavo Tavares, da Costa, Emmerson Corrêa Brasil, Capaccia, Anne Miranda, Mohana-Borges, Ronaldo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281115/ https://www.ncbi.nlm.nih.gov/pubmed/25551442 http://dx.doi.org/10.1371/journal.pone.0115941

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