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NSK-01105, a Novel Sorafenib Derivative, Inhibits Human Prostate Tumor Growth via Suppression of VEGFR2/EGFR-Mediated Angiogenesis

The purpose of this study is to investigate the anti-angiogenic activities of NSK-01105, a novel sorafenib derivative, in in vitro, ex vivo and in vivo models, and explore the potential mechanisms. NSK-01105 significantly inhibited vascular endothelial growth factor (VEGF)-induced migration and tube...

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Detalles Bibliográficos
Autores principales:	Yu, Pengfei, Ye, Liang, Wang, Hongbo, Du, Guangying, Zhang, Jianzhao, Zuo, Yanhua, Zhang, Jinghai, Tian, Jingwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281216/ https://www.ncbi.nlm.nih.gov/pubmed/25551444 http://dx.doi.org/10.1371/journal.pone.0115041

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