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Distinct Regions of the Large Extracellular Domain of Tetraspanin CD9 Are Involved in the Control of Human Multinucleated Giant Cell Formation
Multinucleated giant cells, formed by the fusion of monocytes/macrophages, are features of chronic granulomatous inflammation associated with infections or the persistent presence of foreign material. The tetraspanins CD9 and CD81 regulate multinucleated giant cell formation: soluble recombinant pro...
Autores principales: | Hulme, Rachel S., Higginbottom, Adrian, Palmer, John, Partridge, Lynda J., Monk, Peter N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281222/ https://www.ncbi.nlm.nih.gov/pubmed/25551757 http://dx.doi.org/10.1371/journal.pone.0116289 |
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