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Distinct Regions of the Large Extracellular Domain of Tetraspanin CD9 Are Involved in the Control of Human Multinucleated Giant Cell Formation

Multinucleated giant cells, formed by the fusion of monocytes/macrophages, are features of chronic granulomatous inflammation associated with infections or the persistent presence of foreign material. The tetraspanins CD9 and CD81 regulate multinucleated giant cell formation: soluble recombinant pro...

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Detalles Bibliográficos
Autores principales: Hulme, Rachel S., Higginbottom, Adrian, Palmer, John, Partridge, Lynda J., Monk, Peter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281222/
https://www.ncbi.nlm.nih.gov/pubmed/25551757
http://dx.doi.org/10.1371/journal.pone.0116289

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