Cargando…

Influence of Genetic Variants in TPMT and COMT Associated with Cisplatin Induced Hearing Loss in Patients with Cancer: Two New Cohorts and a Meta-Analysis Reveal Significant Heterogeneity between Cohorts

Treatment with cisplatin-containing chemotherapy regimens causes hearing loss in 40–60% of cancer patients. It has been suggested that genetic variants in the genes encoding thiopurine S-methyltransferase (TPMT) and catechol O-methyltransferase (COMT) can predict the development of cisplatin-induced...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hagleitner, Melanie M., Coenen, Marieke J. H., Patino-Garcia, Ana, de Bont, Eveline S. J. M., Gonzalez-Neira, Anna, Vos, Hanneke I., van Leeuwen, Frank N., Gelderblom, Hans, Hoogerbrugge, Peter M., Guchelaar, Henk-Jan, te Loo, Maroeska W. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281251/ https://www.ncbi.nlm.nih.gov/pubmed/25551397 http://dx.doi.org/10.1371/journal.pone.0115869

Ejemplares similares

Survival Trends and Long-Term Toxicity in Pediatric Patients with Osteosarcoma
por: Hagleitner, Melanie M., et al.
Publicado: (2012)

Analysis of Drug Metabolizing Gene Panel in Osteosarcoma Patients Identifies Association Between Variants in SULT1E1, CYP2B6 and CYP4F8 and Methotrexate Levels and Toxicities
por: Hurkmans, Evelien G. E., et al.
Publicado: (2020)

SLC7A8 coding for LAT2 is associated with early disease progression in osteosarcoma and transports doxorubicin
por: Hurkmans, Evelien G. E., et al.
Publicado: (2022)

Risk factors for thiopurine‐induced myelosuppression and infections in inflammatory bowel disease patients with a normal TPMT genotype
por: Broekman, M. M. T. J., et al.
Publicado: (2017)

Contribution of common and rare genetic variants in CEP72 on vincristine‐induced peripheral neuropathy in brain tumour patients
por: Klumpers, Marije J., et al.
Publicado: (2022)

Thiopurine methyltransferase (TPMT) genotyping to predict myelosuppression risk
por: Nguyen, Christine M., et al.
Publicado: (2011)

In Vitro Protein Stability of Two Naturally Occurring Thiopurine S-Methyltransferase Variants: Biophysical Characterization of TPMT*6 and TPMT*8
por: Wennerstrand, Patricia, et al.
Publicado: (2017)

One amino acid makes a difference–Characterization of a new TPMT allele and the influence of SAM on TPMT stability
por: Iu, Yan Ping Heidi, et al.
Publicado: (2017)

Replication of TPMT and ABCC3 Genetic Variants Highly Associated With Cisplatin-Induced Hearing Loss in Children
por: Pussegoda, K, et al.
Publicado: (2013)

Genome-Wide Analyses of Nephrotoxicity in Platinum-Treated Cancer Patients Identify Association with Genetic Variant in RBMS3 and Acute Kidney Injury
por: Klumpers, Marije J., et al.
Publicado: (2022)

Pharmacogenetics of chemotherapy treatment response and -toxicities in patients with osteosarcoma: a systematic review
por: Hurkmans, Evelien G. E., et al.
Publicado: (2022)

Genes implicated in thiopurine-induced toxicity: Comparing TPMT enzyme activity with clinical phenotype and exome data in a paediatric IBD cohort
por: Coelho, Tracy, et al.
Publicado: (2016)

Pharmacogenetic variants in TPMT alter cellular responses to cisplatin in inner ear cell lines
por: Bhavsar, Amit P., et al.
Publicado: (2017)

Pharmacogenetics of telatinib, a VEGFR-2 and VEGFR-3 tyrosine kinase inhibitor, used in patients with solid tumors
por: Steeghs, Neeltje, et al.
Publicado: (2009)

Association Between Genetically Predicted Expression of TPMT and Azathioprine Adverse Events
por: Davis, Alyssa, et al.
Publicado: (2023)

Implications of Tioguanine Dosing in IBD Patients with a TPMT Deficiency
por: Deben, Debbie S., et al.
Publicado: (2023)

Prospective Validation of a Prognostic Model for Respiratory Syncytial Virus Bronchiolitis in Late Preterm Infants: A Multicenter Birth Cohort Study
por: Blanken, Maarten O., et al.
Publicado: (2013)

Comte
por: Marvin, Francis Sydney, 1863-1943
Publicado: (1941)

Imputation of TPMT defective alleles for the identification of patients with high-risk phenotypes
por: Almoguera, Berta, et al.
Publicado: (2014)

Association of COMT and COMT-DRD2 interaction with creative potential
por: Zhang, Shun, et al.
Publicado: (2014)

Genetic Variants as Predictive Markers for Ototoxicity and Nephrotoxicity in Patients with Locally Advanced Head and Neck Cancer Treated with Cisplatin-Containing Chemoradiotherapy (The PRONE Study)
por: Driessen, Chantal M., et al.
Publicado: (2019)

A low COMT activity haplotype is associated with recurrent preeclampsia in a Norwegian population cohort (HUNT2)
por: Roten, L.T., et al.
Publicado: (2011)

Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia
por: Hurkmans, Evelien G. E., et al.
Publicado: (2023)

The rs1142345 in TPMT Affects the Therapeutic Effect of Traditional Hypoglycemic Herbs in Prediabetes
por: Li, Xi, et al.
Publicado: (2013)

Comparison of TPMT and NUDT15 polymorphisms in Chinese patients with inflammatory bowel disease
por: Wang, Hong-Hui, et al.
Publicado: (2018)

Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier
por: Zhou, Yitian, et al.
Publicado: (2020)

Novel Tetra-Primer ARMS-PCR Assays for Thiopurine Intolerance Susceptibility Mutations NUDT15 c.415C>T and TPMT c.719A>G (TPMT*3C) in East Asians
por: Ho, Chi-Chun, et al.
Publicado: (2017)

Breast density and polymorphisms in genes coding for CYP1A2 and COMT: the Multiethnic Cohort
por: Takata, Yumie, et al.
Publicado: (2007)

Sociologie de Comte
por: Arnaud, Pierre
Publicado: (1969)

Sociología de Comte
por: Arnaud, Pierre
Publicado: (1971)

Thiopurine Drugs in the Treatment of Ulcerative Colitis: Identification of a Novel Deleterious Mutation in TPMT
por: Harmand, Pierre-Olivier, et al.
Publicado: (2020)

Comparison of variants in TPMT and NUDT15 between sequencing and genotyping methods in a multistate pediatric institution
por: Cook, Kelsey J., et al.
Publicado: (2023)

Lack of Association Between COMT and Working Memory in a Population-Based Cohort of Healthy Young Adults
por: Wardle, Margaret C, et al.
Publicado: (2013)

COMT and prenatal maternal smoking in associations with conduct problems and crime: the Pelotas 1993 birth cohort study
por: Salatino-Oliveira, Angélica, et al.
Publicado: (2016)

Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly Specific, Novel Mouse Model of Altered COMT Activity
por: Barkus, Chris, et al.
Publicado: (2016)

Measurements of 6-thioguanine nucleotide levels with TPMT and NUDT15 genotyping in patients with Crohn’s disease
por: Lee, Ji Hyeon, et al.
Publicado: (2017)

Ancestry and TPMT-VNTR Polymorphism: Relationship with Hematological Toxicity in Uruguayan Patients with Acute Lymphoblastic Leukemia
por: Burgueño-Rodríguez, Gabriela, et al.
Publicado: (2020)

The Identification of a Novel Thiopurine S-Methyltransferase Allele, TPMT*45, in Korean Patient with Crohn’s Disease
por: Ha, Changhee, et al.
Publicado: (2020)

Susceptibility to thiopurine toxicity by TPMT and NUDT15 variants in Colombian children with acute lymphoblastic leukemia
por: Correa-Jimenez, Oscar, et al.
Publicado: (2021)

Auguste Comte : los fundamentos de la sociología
por: Comte, Auguste, 1798-1857
Publicado: (1988)

Cannot write session to /tmp/vufind_sessions/sess_qpkr67a88cfqog62i9p014drd0