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Enzymatic DNA oxidation: mechanisms and biological significance

DNA methylation at cytosines (5mC) is a major epigenetic modification involved in the regulation of multiple biological processes in mammals. How methylation is reversed was until recently poorly understood. The family of dioxygenases commonly known as Ten-eleven translocation (Tet) proteins are res...

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Detalles Bibliográficos
Autores principales: Xu, Guo-Liang, Walsh, Colum P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281339/
https://www.ncbi.nlm.nih.gov/pubmed/25341925
http://dx.doi.org/10.5483/BMBRep.2014.47.11.223