The opioid receptor pharmacology of GSK1521498 compared to other ligands with differential effects on compulsive reward-related behaviours

RATIONALE: The novel opioid receptor antagonist, GSK1421498, has been shown to attenuate reward-driven compulsive behaviours, such as stimulant drug seeking or binge eating, in animals and humans. Here, we report new data on the receptor pharmacology of GSK121498, in comparison to naltrexone, naloxo...

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Detalles Bibliográficos
Autores principales: Kelly, Eamonn, Mundell, Stuart J., Sava, Anna, Roth, Adelheid L., Felici, Antonio, Maltby, Kay, Nathan, Pradeep J., Bullmore, Edward T., Henderson, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281354/
https://www.ncbi.nlm.nih.gov/pubmed/24973897
http://dx.doi.org/10.1007/s00213-014-3666-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281354/
https://www.ncbi.nlm.nih.gov/pubmed/24973897
http://dx.doi.org/10.1007/s00213-014-3666-3

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