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Mathematical Modeling of Radiofrequency Ablation for Varicose Veins

We present a three-dimensional mathematical model for the study of radiofrequency ablation (RFA) with blood flow for varicose vein. The model designed to analyze temperature distribution heated by radiofrequency energy and cooled by blood flow includes a cylindrically symmetric blood vessel with a h...

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Detalles Bibliográficos
Autores principales: Choi, Sun Young, Kwak, Byung Kook, Seo, Taewon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281440/
https://www.ncbi.nlm.nih.gov/pubmed/25587351
http://dx.doi.org/10.1155/2014/485353
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author Choi, Sun Young
Kwak, Byung Kook
Seo, Taewon
author_facet Choi, Sun Young
Kwak, Byung Kook
Seo, Taewon
author_sort Choi, Sun Young
collection PubMed
description We present a three-dimensional mathematical model for the study of radiofrequency ablation (RFA) with blood flow for varicose vein. The model designed to analyze temperature distribution heated by radiofrequency energy and cooled by blood flow includes a cylindrically symmetric blood vessel with a homogeneous vein wall. The simulated blood velocity conditions are U = 0, 1, 2.5, 5, 10, 20, and 40 mm/s. The lower the blood velocity, the higher the temperature in the vein wall and the greater the tissue damage. The region that is influenced by temperature in the case of the stagnant flow occupies approximately 28.5% of the whole geometry, while the region that is influenced by temperature in the case of continuously moving electrode against the flow direction is about 50%. The generated RF energy induces a temperature rise of the blood in the lumen and leads to an occlusion of the blood vessel. The result of the study demonstrated that higher blood velocity led to smaller thermal region and lower ablation efficiency. Since the peak temperature along the venous wall depends on the blood velocity and pullback velocity, the temperature distribution in the model influences ablation efficiency. The vein wall absorbs more energy in the low pullback velocity than in the high one.
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spelling pubmed-42814402015-01-13 Mathematical Modeling of Radiofrequency Ablation for Varicose Veins Choi, Sun Young Kwak, Byung Kook Seo, Taewon Comput Math Methods Med Research Article We present a three-dimensional mathematical model for the study of radiofrequency ablation (RFA) with blood flow for varicose vein. The model designed to analyze temperature distribution heated by radiofrequency energy and cooled by blood flow includes a cylindrically symmetric blood vessel with a homogeneous vein wall. The simulated blood velocity conditions are U = 0, 1, 2.5, 5, 10, 20, and 40 mm/s. The lower the blood velocity, the higher the temperature in the vein wall and the greater the tissue damage. The region that is influenced by temperature in the case of the stagnant flow occupies approximately 28.5% of the whole geometry, while the region that is influenced by temperature in the case of continuously moving electrode against the flow direction is about 50%. The generated RF energy induces a temperature rise of the blood in the lumen and leads to an occlusion of the blood vessel. The result of the study demonstrated that higher blood velocity led to smaller thermal region and lower ablation efficiency. Since the peak temperature along the venous wall depends on the blood velocity and pullback velocity, the temperature distribution in the model influences ablation efficiency. The vein wall absorbs more energy in the low pullback velocity than in the high one. Hindawi Publishing Corporation 2014 2014-12-18 /pmc/articles/PMC4281440/ /pubmed/25587351 http://dx.doi.org/10.1155/2014/485353 Text en Copyright © 2014 Sun Young Choi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Choi, Sun Young
Kwak, Byung Kook
Seo, Taewon
Mathematical Modeling of Radiofrequency Ablation for Varicose Veins
title Mathematical Modeling of Radiofrequency Ablation for Varicose Veins
title_full Mathematical Modeling of Radiofrequency Ablation for Varicose Veins
title_fullStr Mathematical Modeling of Radiofrequency Ablation for Varicose Veins
title_full_unstemmed Mathematical Modeling of Radiofrequency Ablation for Varicose Veins
title_short Mathematical Modeling of Radiofrequency Ablation for Varicose Veins
title_sort mathematical modeling of radiofrequency ablation for varicose veins
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281440/
https://www.ncbi.nlm.nih.gov/pubmed/25587351
http://dx.doi.org/10.1155/2014/485353
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