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A novel mechanism for Prp5 function in prespliceosome formation and proofreading the branch site sequence
The DEAD-box RNA helicase Prp5 is required for the formation of the prespliceosome through an ATP-dependent function to remodel U2 small nuclear ribonucleoprotein particles (snRNPs) and an ATP-independent function of unknown mechanism. Prp5 has also been implicated in proofreading the branch site se...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281567/ https://www.ncbi.nlm.nih.gov/pubmed/25561497 http://dx.doi.org/10.1101/gad.253708.114 |