Intestinal epithelial suppressor of cytokine signaling 3 enhances microbial-induced inflammatory tumor necrosis factor-α, contributing to epithelial barrier dysfunction

A single layer of intestinal epithelial cells (IEC) lines the entire gastrointestinal tract and provides the first line of defense and barrier against an abundance of microbial stimuli. IEC homeostasis and repair are mediated through microbe-sensing Toll-like receptor (TLR)-induced inflammatory path...

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Detalles Bibliográficos
Autores principales: Thagia, Imtiyaz, Shaw, Elisabeth J., Smith, Emily, Else, Kathryn J., Rigby, Rachael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2014
Materias:
Inflammation/Immunity/Mediators
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281689/
https://www.ncbi.nlm.nih.gov/pubmed/25377316
http://dx.doi.org/10.1152/ajpgi.00214.2014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281689/
https://www.ncbi.nlm.nih.gov/pubmed/25377316
http://dx.doi.org/10.1152/ajpgi.00214.2014

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